THE STEM – PD CLINICAL TRIAL

The overall goal of the STEM-PD trial is to
treat the main motor symptoms of PD,
which are caused by a lack of dopamine
in the brain.

Introduction

STEM-PD is a clinical trial run by clinical and preclinical research teams in Sweden and the UK. The goal of the trial is to develop a safe and efficacious stem cell-based treatment for Parkinson’s disease. The trial involves transplantation of stem cell-derived dopamine STEM-PD cells into the brains of Parkinson’s disease patients. The stem cell…

What is the STEM-PD Trial?

The STEM-PD trial is a multicentre (Sweden and UK), single arm (treatment only) trial that will assess the safety of escalating doses of stem cell-derived dopamine progenitors. Four patients will be transplanted with the first dose, and once all four patients have completed 6 months follow up, an evaluation will be performed to assess if…

Why develop a stem cell therapy for Parkinson’s disease?

Parkinson’s disease (PD) is a progressive neurodegenerative condition that is classically characterised by slowness of movement, unstable gait, stiff muscles, and tremor. These motor symptoms are caused by the loss of a specific type of neurons which produce and release a chemical called dopamine. As the dopamine-producing neurons are progressively lost, the motor symptoms of…